FREM1 anticorps

N° du produit ABIN7259276

Détail du produit anti-FREM1 anticorps

Antigène: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FREM1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human FREM1 (NP_659403.4).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FREM1

Antigène: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Autre désignation: FREM1 (FREM1 Produits)

Synonymes: anticorps BNAR, anticorps C9orf143, anticorps C9orf145, anticorps C9orf154, anticorps MOTA, anticorps TILRR, anticorps TRIGNO2, anticorps RGD1306981, anticorps BC037594, anticorps D430009N09, anticorps D630008K06, anticorps eye, anticorps eyes2, anticorps heb, anticorps qbrick, anticorps FRAS1 related extracellular matrix 1, anticorps Fras1 related extracellular matrix 1, anticorps Fras1 related extracellular matrix protein 1, anticorps FREM1, anticorps Frem1

Sujet: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Poids moléculaire:

Observed_MW: 72 kDa

Calculated_MW: 25 kDa/42 kDa/80 kDa/244 kDa

ID gène: 158326

UniProt: Q5H8C1