GRK2 anticorps
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- Antigène Voir toutes GRK2 (ADRBK1) Anticorps
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GRK2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- This antibody ist KO validated.
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant fusion protein of human ADRBK1 (NP_001610.2).
- Isotype
- IgG
- Top Product
- Discover our top product ADRBK1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Autre désignation
- ADRBK1 (ADRBK1 Produits)
- Synonymes
- anticorps Adrbk-1, anticorps Bark-1, anticorps GRK2, anticorps betaARK1, anticorps BARK1, anticorps BETA-ARK1, anticorps GRK-2, anticorps Grk2, anticorps beta-adrenergic receptor kinase 1, anticorps G protein-coupled receptor kinase 2, anticorps Tsp_00497, anticorps grk2, anticorps Grk2, anticorps GRK2
- Sujet
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
- Poids moléculaire
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Observed_MW: 80 kDa
Calculated_MW: 79 kDa
- ID gène
- 156
- UniProt
- P25098
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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