TXNRD1 anticorps

N° du produit ABIN7259296

Détail du produit anti-TXNRD1 anticorps

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNRD1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human TXNRD1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TXNRD1

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Autre désignation: TXNRD1 (TXNRD1 Produits)

Synonymes: anticorps TrxR1, anticorps cb682, anticorps fb83a08, anticorps wu:fb83a08, anticorps GB14972, anticorps MGC85342, anticorps NADPH-dependent thioredoxin reductase C, anticorps T32G6.20, anticorps T32G6_20, anticorps GRIM-12, anticorps TR, anticorps TR1, anticorps TRXR1, anticorps TXNR, anticorps Tr, anticorps thioredoxin reductase 1, anticorps thioredoxin reductase 1 L homeolog, anticorps NADPH-dependent thioredoxin reductase C, anticorps ThioRedoXin Reductase, anticorps TXNRD1, anticorps txnrd1, anticorps Trxr-1, anticorps txnrd1.L, anticorps NTRC, anticorps trxr-1, anticorps Txnrd1

Sujet: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

ID gène: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis