Asialoglycoprotein Receptor 1 anticorps

N° du produit ABIN7259372

Détail du produit anti-Asialoglycoprotein Receptor 1 anticorps

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ASGR1.

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Asialoglycoprotein Receptor 1

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Autre désignation: ASGR1 (ASGR1 Produits)

Synonymes: anticorps ASGR1, anticorps ASGPR, anticorps ASGPR1, anticorps CLEC4H1, anticorps HL-1, anticorps Asgr, anticorps Asgr-1, anticorps ASGR, anticorps RATRHL1, anticorps RHL1, anticorps asialoglycoprotein receptor 1, anticorps LOC721786, anticorps ASGR1, anticorps LOC489461, anticorps Asgr1, anticorps LOC101116157

Sujet: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

ID gène: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis