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CD59 anticorps

CD59 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7259438
  • Antigène Voir toutes CD59 Anticorps
    CD59
    Reactivité
    • 140
    • 13
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 89
    • 72
    • 6
    • 4
    Lapin
    Clonalité
    • 94
    • 74
    • 1
    Polyclonal
    Conjugué
    • 76
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD59 est non-conjugé
    Application
    • 99
    • 67
    • 44
    • 40
    • 31
    • 27
    • 25
    • 15
    • 14
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human CD59
    Isotype
    IgG
    Top Product
    Discover our top product CD59 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CD59
    Autre désignation
    CD59 (CD59 Produits)
    Synonymes
    anticorps 16.3A5, anticorps 1F5, anticorps EJ16, anticorps EJ30, anticorps EL32, anticorps G344, anticorps HRF-20, anticorps HRF20, anticorps MAC-IP, anticorps MACIF, anticorps MEM43, anticorps MIC11, anticorps MIN1, anticorps MIN2, anticorps MIN3, anticorps MIRL, anticorps MSK21, anticorps p18-20, anticorps Cd59a, anticorps Cd59b, anticorps MACIP, anticorps CD59 molecule (CD59 blood group), anticorps CD59 molecule, anticorps CD59, anticorps Cd59
    Sujet
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    ID gène
    966
    UniProt
    P13987
    Pathways
    Système du Complément
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