MED1 anticorps

N° du produit ABIN7259644

Détail du produit anti-MED1 anticorps

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MED1 (NP_004765.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: MED1 (MED1 Produits)

Synonymes: anticorps CRSP1, anticorps CRSP200, anticorps DRIP205, anticorps DRIP230, anticorps PBP, anticorps PPARBP, anticorps PPARGBP, anticorps RB18A, anticorps TRAP220, anticorps TRIP2, anticorps CRSP-1, anticorps MED1, anticorps pbp, anticorps nbr1, anticorps crsp1, anticorps rb18a, anticorps trip2, anticorps pparbp, anticorps crsp200, anticorps drip205, anticorps drip230, anticorps ppargbp, anticorps trap220, anticorps CG7162, anticorps Dmel\\CG7162, anticorps Med1, anticorps Med1/SOP3/TRAP220, anticorps Trap220, anticorps dTRAP220, anticorps AI480703, anticorps CRSP210, anticorps Pparbp, anticorps l11Jus15, anticorps RGD1559552, anticorps mediator complex subunit 1, anticorps calcitonin-related polypeptide beta, anticorps Mediator complex subunit 1, anticorps mediator of RNA polymerase II transcription subunit 1, anticorps MED1, anticorps CALCB, anticorps med1, anticorps Med1

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Poids moléculaire:

Observed_MW: 160 kDa

Calculated_MW: 61 kDa/168 kDa

ID gène: 5469

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha