AIRE anticorps
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- Antigène Voir toutes AIRE Anticorps
- AIRE (Autoimmune Regulator (AIRE))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AIRE est non-conjugé
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Application
- Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human AIRE (NP_000374.1).
- Isotype
- IgG
- Top Product
- Discover our top product AIRE Anticorps primaire
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- Indications d'application
- IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- AIRE (Autoimmune Regulator (AIRE))
- Autre désignation
- AIRE (AIRE Produits)
- Sujet
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- ID gène
- 326
- UniProt
- O43918
- Pathways
- Chromatin Binding
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