PTBP1 anticorps

N° du produit ABIN7009783

Détail du produit anti-PTBP1 anticorps

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PTBP1 (NP_114368.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTBP1

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Autre désignation: PTBP1 (PTBP1 Produits)

Synonymes: anticorps HNRNP-I, anticorps HNRNPI, anticorps HNRPI, anticorps PTB, anticorps PTB-1, anticorps PTB-T, anticorps PTB2, anticorps PTB3, anticorps PTB4, anticorps pPTB, anticorps Ptb, anticorps hnrpi, anticorps hnrnp-I, anticorps vgrbp60, anticorps AA407203, anticorps AL033359, anticorps Pybp, anticorps Pybp1, anticorps Pybp2, anticorps ptbp1, anticorps wu:fb99f12, anticorps zgc:110689, anticorps ptb, anticorps ATPTB1, anticorps POLYPYRIMIDINE TRACT-BINDING, anticorps POLYPYRIMIDINE TRACT-BINDING PROTEIN 1, anticorps T4P13.16, anticorps T4P13_16, anticorps polypyrimidine tract-binding protein 1, anticorps PTBP1, anticorps polypyrimidine tract binding protein 1, anticorps polypyrimidine tract binding protein 1 S homeolog, anticorps polypyrimidine tract-binding protein, anticorps polypyrimidine tract binding protein 1a, anticorps polypyrimidine tract binding protein 1 L homeolog, anticorps polypyrimidine tract-binding protein 1, anticorps PTBP1, anticorps ptbp1.S, anticorps NAEGRDRAFT_80143, anticorps LOC100285404, anticorps Ptbp1, anticorps ptbp1a, anticorps ptbp1.L, anticorps PTB1, anticorps LOC100061673

Sujet: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire:

Observed_MW: 64 kDa

Calculated_MW: 57 kDa/59 kDa

ID gène: 5725

UniProt: P26599

Pathways: Regulation of Muscle Cell Differentiation