DKC1 anticorps

N° du produit ABIN7259883

Détail du produit anti-DKC1 anticorps

Antigène: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKC1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DKC1 (NP_001354.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DKC1

Antigène: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Autre désignation: DKC1 (DKC1 Produits)

Synonymes: anticorps CBF5, anticorps DKC, anticorps DKCX, anticorps NAP57, anticorps NOLA4, anticorps XAP101, anticorps dyskerin, anticorps fv62a07, anticorps wu:fa28f10, anticorps wu:fc87a02, anticorps wu:fi24a05, anticorps wu:fv62a07, anticorps zgc:110395, anticorps DKC1, anticorps cbf5, anticorps dkc, anticorps nap57, anticorps nola4, anticorps xap101, anticorps BC068171, anticorps Nap57, anticorps AtCBF5, anticorps AtNAP57, anticorps homologue of NAP57, anticorps dyskerin pseudouridine synthase 1, anticorps microRNA 664b, anticorps dyskeratosis congenita 1, dyskerin, anticorps dyskeratosis congenita 1, dyskerin L homeolog, anticorps homologue of NAP57, anticorps DKC1, anticorps MIR664B, anticorps dkc1, anticorps dkc1.L, anticorps Dkc1, anticorps NAP57

Sujet: This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.

ID gène: 1736

UniProt: O60832

Pathways: Telomere Maintenance