PITX2 anticorps

N° du produit ABIN7259893

Détail du produit anti-PITX2 anticorps

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITX2 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human PITX2 (NP_000316.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PITX2

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Autre désignation: PITX2 (PITX2 Produits)

Synonymes: anticorps ARP1, anticorps Brx1, anticorps IDG2, anticorps IGDS, anticorps IGDS2, anticorps IHG2, anticorps IRID2, anticorps Otlx2, anticorps PTX2, anticorps RGS, anticorps RIEG, anticorps RIEG1, anticorps RS, anticorps 9430085M16Rik, anticorps Brx1a, anticorps Brx1b, anticorps Munc30, anticorps Pitx2a, anticorps Pitx2b, anticorps Pitx2c, anticorps Pitx2cbeta, anticorps Ptx2, anticorps Rieg, anticorps pitx2a, anticorps pitx2c, anticorps zgc:110508, anticorps XPtx2b, anticorps xPtx2, anticorps xpitx2, anticorps arp1, anticorps brx1, anticorps idg2, anticorps igds, anticorps igds2, anticorps ihg2, anticorps irid2, anticorps otlx2, anticorps pitx2-A, anticorps ptx2, anticorps rgs, anticorps rieg, anticorps rieg1, anticorps pitx-2, anticorps pitx2, anticorps paired like homeodomain 2, anticorps paired-like homeodomain transcription factor 2, anticorps paired-like homeodomain 2, anticorps paired like homeodomain 2 S homeolog, anticorps paired like homeodomain 2 L homeolog, anticorps PITX2, anticorps Pitx2, anticorps pitx2, anticorps pitx2.S, anticorps pitx2.L

Sujet: This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Poids moléculaire:

Observed_MW: 39 kDa

Calculated_MW: 30 kDa/35 kDa

ID gène: 5308

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development