TAPBP anticorps

N° du produit ABIN7260003

Détail du produit anti-TAPBP anticorps

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TAPBP (NP_757345.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP (TAPBP Produits)

Synonymes: anticorps SI:dZ179B20.1, anticorps SI:dZ179B20.3, anticorps SI:dZ179B20.7, anticorps mhc1uda, anticorps mhc1ufa, anticorps tpsn, anticorps zgc:109814, anticorps tapbp, anticorps TAPBP, anticorps D17Wsu91e, anticorps TPN, anticorps NGS17, anticorps TAPA, anticorps TPSN, anticorps TAP binding protein (tapasin), tandem duplicate 1, anticorps TAP binding protein, anticorps tapbp.1, anticorps tapbp, anticorps TAPBP, anticorps Tapbp

Sujet: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 48 kDa

Calculated_MW: 38 kDa/43 kDa/47 kDa/53 kDa

ID gène: 6892

UniProt: O15533