Chitotriosidase 1 anticorps

N° du produit ABIN7260061

Détail du produit anti-Chitotriosidase 1 anticorps

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chitotriosidase 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CHIT1 (NP_003456.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Chitotriosidase 1

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Autre désignation: CHIT1 (CHIT1 Produits)

Synonymes: anticorps CHI3, anticorps CHIT, anticorps CHITD, anticorps CHIT1, anticorps chio, anticorps 2300002L19Rik, anticorps chitinase 1, anticorps chitinase 1 (chitotriosidase), anticorps CHIT1, anticorps chit1, anticorps Chit1

Sujet: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

ID gène: 1118

UniProt: Q13231