Interleukin enhancer-binding factor 3 (ILF3) anticorps

N° du produit ABIN7260443

Détail du produit

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ILF3 (NP_036350.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Autre désignation: ILF3 (ILF3 Produits)

Synonymes: anticorps CBTF, anticorps DRBF, anticorps DRBP76, anticorps MMP4, anticorps MPHOSPH4, anticorps MPP4, anticorps NF-AT-90, anticorps NF110, anticorps NF110b, anticorps NF90, anticorps NF90a, anticorps NF90b, anticorps NFAR, anticorps NFAR-1, anticorps NFAR2, anticorps TCP110, anticorps TCP80, anticorps MBII-26, anticorps ilf3, anticorps wu:fb37d07, anticorps wu:fb94b02, anticorps zgc:77030, anticorps 4F.1, anticorps cbtf122, anticorps ilf3-A, anticorps ubp3, anticorps ubp4, anticorps xilf3, anticorps interleukin enhancer binding factor 3, anticorps interleukin enhancer binding factor 3b, anticorps interleukin enhancer binding factor 3 S homeolog, anticorps ILF3, anticorps Ilf3, anticorps ilf3b, anticorps ilf3.S

Sujet: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 95 kDa/120 kDa

Calculated_MW: 74 kDa/75 kDa/76 kDa/82 kDa/95 kDa

ID gène: 3609

UniProt: Q12906

Pathways: M Phase