MMP14 anticorps

N° du produit ABIN7260517

Détail du produit anti-MMP14 anticorps

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human MT1-MMP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MT1-MMP (MMP14 Produits)

Synonymes: anticorps MMP1, anticorps MMP-14, anticorps MMP-X1, anticorps MT-MMP, anticorps MT-MMP 1, anticorps MT1-MMP, anticorps MT1MMP, anticorps MTMMP1, anticorps mmp-x1, anticorps mt1-mmp, anticorps mtmmp1, anticorps AI325305, anticorps MT-MMP-1, anticorps sabe, anticorps Mt1-mmp, anticorps MT-MMPbeta, anticorps cb386, anticorps sb:cb386, anticorps wu:fb72b09, anticorps mmp14, anticorps matrix metallopeptidase 14, anticorps matrix metallopeptidase 14 (membrane-inserted), anticorps matrix metallopeptidase 14b (membrane-inserted), anticorps matrix metallopeptidase 14a (membrane-inserted), anticorps matrix metallopeptidase 14 L homeolog, anticorps MMP14, anticorps mmp14, anticorps Mmp14, anticorps mmp14b, anticorps mmp14a, anticorps mmp14.L

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

ID gène: 4323

UniProt: P50281

Pathways: Autophagy