Claudin 11 anticorps

N° du produit ABIN7260581

Détail du produit anti-Claudin 11 anticorps

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CLDN11 (NP_005593.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:20-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: CLDN11 (CLDN11 Produits)

Synonymes: anticorps cldn11, anticorps fb97c11, anticorps wu:fb97c11, anticorps claudin-11, anticorps CLDN11, anticorps Claudin-11, anticorps DKFZp459H2322, anticorps OSP, anticorps OTM, anticorps Claudin11, anticorps Osp, anticorps Otm, anticorps claudin 11b, anticorps claudin 11, anticorps cldn11b, anticorps CLDN11, anticorps Cldn11

Sujet: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

ID gène: 5010

UniProt: O75508

Pathways: Hepatitis C