anticorps EB1, anticorps 5530600P05Rik, anticorps AI462499, anticorps AI504412, anticorps AW260097, anticorps BIM1p, anticorps D2Ertd459e, anticorps Eb1, anticorps MAPRE1, anticorps mapre1l, anticorps wu:fi33c06, anticorps zgc:55428, anticorps zgc:77807, anticorps mapre1, anticorps wu:fa01e12, anticorps wu:fc23e11, anticorps zgc:85755, anticorps MGC52508, anticorps eb1, anticorps xEB1B, anticorps Mapre3, anticorps microtubule associated protein RP/EB family member 1, anticorps microtubule-associated protein, RP/EB family, member 1, anticorps microtubule-associated protein, RP/EB family, member 1a, anticorps microtubule-associated protein, RP/EB family, member 1b, anticorps microtubule associated protein RP/EB family member 1 L homeolog, anticorps microtubule associated protein RP/EB family member 1 S homeolog, anticorps MAPRE1, anticorps Mapre1, anticorps mapre1a, anticorps mapre1b, anticorps mapre1.L, anticorps mapre1.S
Sujet
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.