MAPKBP1 anticorps

N° du produit ABIN7260601

Détail du produit anti-MAPKBP1 anticorps

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKBP1 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human MAPKBP1 (NP_001122080.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MAPKBP1

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Autre désignation: MAPKBP1 (MAPKBP1 Produits)

Synonymes: anticorps MGC83682, anticorps JNKBP-1, anticorps 2810483F24Rik, anticorps AW123212, anticorps Jnkbp1, anticorps mKIAA0596, anticorps mitogen-activated protein kinase binding protein 1 L homeolog, anticorps mitogen-activated protein kinase binding protein 1, anticorps mitogen activated protein kinase binding protein 1, anticorps mapkbp1.L, anticorps MAPKBP1, anticorps Mapkbp1

Sujet: This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.

ID gène: 23005

UniProt: O60336