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GRM8 anticorps

GRM8 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7260739
  • Antigène Voir toutes GRM8 Anticorps
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    Reactivité
    • 30
    • 22
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 27
    • 3
    Lapin
    Clonalité
    • 28
    • 2
    Polyclonal
    Conjugué
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRM8 est non-conjugé
    Application
    • 18
    • 13
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human GRM8
    Isotype
    IgG
    Top Product
    Discover our top product GRM8 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    Autre désignation
    GRM8 (GRM8 Produits)
    Synonymes
    anticorps mGluR8, anticorps GRM8, anticorps MGLUR8, anticorps GLUR8, anticorps GPRC1H, anticorps mGlu8, anticorps A230002O04, anticorps Gprc1h, anticorps Glur8, anticorps Mglur8, anticorps mGluR8b, anticorps mGlur, anticorps glutamate metabotropic receptor 8, anticorps metabotropic glutamate receptor 8, anticorps glutamate receptor, metabotropic 8, anticorps GRM8, anticorps MGLUR8, anticorps LOAG_14062, anticorps Grm8
    Sujet
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Poids moléculaire

    Observed_MW: 120 kDa

    Calculated_MW: 55 kDa/101 kDa

    ID gène
    2918
    UniProt
    O00222
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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