Bestrophin 1 anticorps

N° du produit ABIN7260777

Détail du produit anti-Bestrophin 1 anticorps

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human BEST1 (NP_004174.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: BEST1 (BEST1 Produits)

Synonymes: anticorps CG6264, anticorps Dbest, anticorps Dmel\\CG6264, anticorps anon-WO0118547.380, anticorps best, anticorps dBest1, anticorps dbest1, anticorps dmBest1, anticorps BEST1, anticorps VMD2, anticorps best-1, anticorps ARB, anticorps BEST, anticorps BMD, anticorps RP50, anticorps TU15B, anticorps Bmd, anticorps Vmd2, anticorps mBest1, anticorps Bestrophin 1, anticorps bestrophin 1, anticorps Best1, anticorps BEST1, anticorps best1, anticorps Bm1_25500

Sujet: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 70 kDa

Calculated_MW: 57 kDa/67 kDa/69 kDa

ID gène: 7439

UniProt: O76090