NBR1 anticorps

N° du produit ABIN7010379

Détail du produit anti-NBR1 anticorps

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NBR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human NBR1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NBR1

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Autre désignation: NBR1 (NBR1 Produits)

Synonymes: anticorps fa99f08, anticorps wu:fa99f08, anticorps MGC69008, anticorps NBR1, anticorps 1A1-3B, anticorps M17S2, anticorps mKIAA0049, anticorps Ca125, anticorps RGD1311421, anticorps neighbor of brca1 gene 1a, anticorps neighbor of BRCA1 gene 1 L homeolog, anticorps NBR1, autophagy cargo receptor, anticorps neighbor of Brca1 gene 1, anticorps nbr1a, anticorps nbr1.L, anticorps NBR1, anticorps Nbr1

Sujet: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

ID gène: 4077

UniProt: Q14596

Pathways: Autophagy