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IFITM1 anticorps

IFITM1 Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7260992
  • Antigène Voir toutes IFITM1 Anticorps
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Reactivité
    • 50
    • 5
    • 4
    Humain, Souris
    Hôte
    • 45
    • 4
    • 1
    Lapin
    Clonalité
    • 47
    • 3
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IFITM1 est non-conjugé
    Application
    • 37
    • 26
    • 9
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human IFITM1 (NP_003632.3).
    Isotype
    IgG
    Top Product
    Discover our top product IFITM1 Anticorps primaire
  • Indications d'application
    WB 1:200-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Autre désignation
    IFITM1 (IFITM1 Produits)
    Synonymes
    anticorps 9-27, anticorps CD225, anticorps DSPA2a, anticorps IFI17, anticorps LEU13, anticorps 1110036C17Rik, anticorps Mil-2, anticorps Mil2, anticorps interferon induced transmembrane protein 1, anticorps interferon induced transmembrane protein 1 (9-27), anticorps Ifitm1, anticorps IFITM1
    Sujet
    Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
    Poids moléculaire

    Observed_MW: 17 kDa

    Calculated_MW: 13 kDa

    ID gène
    8519
    UniProt
    P13164
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