NAE1 anticorps

N° du produit ABIN7260999

Détail du produit anti-NAE1 anticorps

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAE1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human NAE1 (NP_003896.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NAE1

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Autre désignation: NAE1 (NAE1 Produits)

Synonymes: anticorps APPBP1, anticorps CG7828, anticorps Dmel\\CG7828, anticorps anon-WO0140519.225, anticorps dAPP-BP1, anticorps dAPPBP1, anticorps A-116A10.1, anticorps ula-1, anticorps Appbp1, anticorps 59kDa, anticorps appbp1, anticorps zgc:66148, anticorps beta-Amyloid precursor protein binding protein 1, anticorps NEDD8 activating enzyme E1 subunit 1, anticorps NEDD8 activating enzyme E1 subunit 1 S homeolog, anticorps nedd8 activating enzyme E1 subunit 1, anticorps NEDD8-activating enzyme E1 regulatory subunit, anticorps APP-BP1, anticorps NAE1, anticorps Nae1, anticorps nae1.S, anticorps nae1, anticorps ula-1

Sujet: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 60 kDa

Calculated_MW: 50 kDa/59 kDa/60 kDa

ID gène: 8883

UniProt: Q13564