PIDD anticorps

N° du produit ABIN7261141

Détail du produit anti-PIDD anticorps

Antigène: PIDD (P53-Induced Death Domain Protein (PIDD))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIDD est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PIDD (NP_665893.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PIDD

Antigène: PIDD (P53-Induced Death Domain Protein (PIDD))

Autre désignation: PIDD (PIDD Produits)

Synonymes: anticorps 1200011D09Rik, anticorps AU042446, anticorps Pidd, anticorps LRDD, anticorps Lrdd, anticorps p53 induced death domain protein 1, anticorps p53-induced death domain protein 1, anticorps Pidd1, anticorps PIDD1

Sujet: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 100-110 kDa

Calculated_MW: 33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

ID gène: 55367

UniProt: Q9HB75

Pathways: Signalisation p53, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity