PCDHA6 anticorps

N° du produit ABIN7261149

Détail du produit anti-PCDHA6 anticorps

Antigène: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA6 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PCDHA6 (NP_061732.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCDHA6

Antigène: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Autre désignation: PCDHA6 (PCDHA6 Produits)

Synonymes: anticorps CNR2, anticorps CNRN2, anticorps CNRS2, anticorps CRNR2, anticorps PCDH-ALPHA6, anticorps CNR, anticorps Cnr2, anticorps Crnr2, anticorps rCNRv06, anticorps PCDHA3, anticorps PCDHA6, anticorps PCDHA7, anticorps PCDHA9, anticorps protocadherin alpha 6, anticorps PCDHA6, anticorps Pcdha6

Sujet: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

ID gène: 56142

UniProt: Q9UN73