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MCM10 anticorps

MCM10 Reactivité: Humain, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7261385
  • Antigène Voir toutes MCM10 Anticorps
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    Reactivité
    • 25
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 24
    • 1
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCM10 est non-conjugé
    Application
    • 16
    • 5
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human MCM10 (NP_877428.1).
    Isotype
    IgG
    Top Product
    Discover our top product MCM10 Anticorps primaire
  • Indications d'application
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    Autre désignation
    MCM10 (MCM10 Produits)
    Synonymes
    anticorps CG9241, anticorps DmMCM10, anticorps Dmel\\CG9241, anticorps Scim19, anticorps mcm10, anticorps CNA43, anticorps DNA43, anticorps xmcm10, anticorps 2410041F14Rik, anticorps AU018508, anticorps C330019M07Rik, anticorps C79164, anticorps Minichromosome maintenance 10, anticorps minichromosome maintenance 10 replication initiation factor, anticorps minichromosome maintenance 10 replication initiation factor L homeolog, anticorps Mcm10, anticorps MCM10, anticorps mcm10.L
    Sujet
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
    ID gène
    55388
    UniProt
    Q7L590
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication
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