LITAF anticorps
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- Antigène Voir toutes LITAF Anticorps
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LITAF est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- This antibody ist KO validated.
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant fusion protein of human LITAF (NP_004853.2).
- Isotype
- IgG
- Top Product
- Discover our top product LITAF Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
- Autre désignation
- LITAF (LITAF Produits)
- Synonymes
- anticorps PIG7, anticorps SIMPLE, anticorps TP53I7, anticorps EET-1, anticorps Pig7, anticorps TNF-alpha, anticorps 3222402J11Rik, anticorps C85531, anticorps N4WBP3, anticorps TBX1, anticorps lipopolysaccharide induced TNF factor, anticorps lipopolysaccharide-induced TNF factor, anticorps LPS-induced TN factor, anticorps LITAF, anticorps Litaf
- Sujet
- Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
- Poids moléculaire
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Observed_MW: 20 kDa
Calculated_MW: 15 kDa/17 kDa/23 kDa
- ID gène
- 9516
- UniProt
- Q99732
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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