ERCC2 anticorps

N° du produit ABIN7261588

Détail du produit anti-ERCC2 anticorps

Antigène: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC2 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ERCC2 (NP_001124339.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ERCC2

Antigène: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Autre désignation: ERCC2 (ERCC2 Produits)

Synonymes: anticorps COFS2, anticorps EM9, anticorps TTD, anticorps XPD, anticorps AA407812, anticorps AU020867, anticorps AW240756, anticorps CXPD, anticorps Ercc-2, anticorps MGC89573, anticorps CG9433, anticorps DhR3, anticorps DhXPD, anticorps DmXPD, anticorps Dmel\\CG9433, anticorps ERCC2, anticorps XPD/ERCC2, anticorps l(2)SH2 2137, anticorps l(2)SH2137, anticorps xpd, anticorps zgc:56365, anticorps ERCC excision repair 2, TFIIH core complex helicase subunit, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 2, anticorps excision repair cross-complementation group 2, anticorps Xeroderma pigmentosum D, anticorps ERCC2, anticorps Ercc2, anticorps ercc2, anticorps Xpd

Sujet: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

ID gène: 2068

UniProt: P18074

Pathways: Réparation de l'ADN