Serotonin Receptor 2B anticorps

N° du produit ABIN7261616

Détail du produit anti-Serotonin Receptor 2B anticorps

Antigène: Serotonin Receptor 2B (HTR2B)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 2B est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human HTR2B (NP_000858.3).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Serotonin Receptor 2B

Antigène: Serotonin Receptor 2B (HTR2B)

Autre désignation: HTR2B (HTR2B Produits)

Synonymes: anticorps 5-HT2B, anticorps 5HT2B, anticorps 5htr2b, anticorps HTR2B, anticorps 5ht2b, anticorps zgc:194094, anticorps zgc:194119, anticorps AJ012488, anticorps AV377389, anticorps 5-HT(2B), anticorps 5-hydroxytryptamine receptor 2B, anticorps 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, anticorps 5-hydroxytryptamine (serotonin) receptor 2B, anticorps HTR2B, anticorps htr2b, anticorps Htr2b

Sujet: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

ID gène: 3357

UniProt: P41595

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process