ILF2 anticorps

N° du produit ABIN7261836

Détail du produit anti-ILF2 anticorps

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILF2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ILF2 (NP_004506.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ILF2

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Autre désignation: ILF2 (ILF2 Produits)

Synonymes: anticorps nf45, anticorps pro3063, anticorps ILF2, anticorps wu:fb34h01, anticorps zgc:73084, anticorps zgc:77276, anticorps NF45, anticorps PRO3063, anticorps 6230405A16Rik, anticorps TEG-267, anticorps Tex261, anticorps Tex267, anticorps interleukin enhancer binding factor 2, anticorps interleukin enhancer binding factor 2 L homeolog, anticorps ilf2, anticorps ILF2, anticorps ilf2.L, anticorps Ilf2

Sujet: The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

ID gène: 3608

UniProt: Q12905