TADA3L anticorps

N° du produit ABIN7262044

Détail du produit anti-TADA3L anticorps

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TADA3L est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TADA3 (NP_597814.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TADA3L

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Autre désignation: TADA3 (TADA3 Produits)

Synonymes: anticorps ADA3, anticorps NGG1, anticorps STAF54, anticorps TADA3L, anticorps hADA3, anticorps Tada3l, anticorps 1110004B19Rik, anticorps AI987856, anticorps fa03f04, anticorps tada3, anticorps wu:fa03f04, anticorps zgc:63596, anticorps ada3, anticorps ada3-A, anticorps ngg1, anticorps tada3l, anticorps tada3l-a, anticorps ada3-B, anticorps tada3l-B, anticorps transcriptional adaptor 3, anticorps transcriptional adapter 3 pseudogene, anticorps transcriptional adaptor 3 (NGG1 homolog, yeast)-like, anticorps transcriptional adaptor 3 L homeolog, anticorps transcriptional adaptor 3 S homeolog, anticorps TADA3, anticorps Tada3, anticorps LOC732883, anticorps LOC100061462, anticorps tada3, anticorps LOC100619707, anticorps tada3l, anticorps tada3.L, anticorps tada3.S

Sujet: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.

ID gène: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway