RAD51 anticorps

N° du produit ABIN7262080

Détail du produit anti-RAD51 anticorps

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human RAD51 (NP_002866.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD51

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: RAD51 (RAD51 Produits)

Synonymes: anticorps BRCC5, anticorps HRAD51, anticorps HsRad51, anticorps HsT16930, anticorps MRMV2, anticorps RAD51A, anticorps RECA, anticorps CRAD51, anticorps wu:fb38e12, anticorps zgc:77754, anticorps RGD1563603, anticorps ATRAD51, anticorps F22D1.20, anticorps F22D1_20, anticorps RAS associated with diabetes protein 51, anticorps AV304093, anticorps Rad51a, anticorps Reca, anticorps brcc5, anticorps rad51, anticorps rad51a, anticorps reca, anticorps xrad51, anticorps RAD51 recombinase, anticorps RAS associated with diabetes protein 51, anticorps RAD51 recombinase L homeolog, anticorps RAD51, anticorps rad51, anticorps Rad51, anticorps rad51.L

Sujet: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 37 kDa

Calculated_MW: 26 kDa/31 kDa/36 kDa

ID gène: 5888

UniProt: Q06609

Pathways: Réparation de l'ADN