LIMS1 anticorps

N° du produit ABIN7011076

Détail du produit anti-LIMS1 anticorps

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMS1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human LIMS1 (NP_001180417.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LIMS1

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Autre désignation: LIMS1 (LIMS1 Produits)

Synonymes: anticorps PINCH, anticorps PINCH-1, anticorps PINCH1, anticorps Pinch1, anticorps RGD1560732, anticorps LIMS3, anticorps LIMS3L, anticorps 2310016J22Rik, anticorps 4921524A02Rik, anticorps AI507642, anticorps AU021743, anticorps AW551584, anticorps C430041B13Rik, anticorps Lims1l, anticorps LIM zinc finger domain containing 1, anticorps LIM and senescent cell antigen-like domains 1, anticorps LIMS1, anticorps Lims1

Sujet: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 40 kDa

Calculated_MW: 37 kDa/38 kDa/41 kDa/44 kDa

ID gène: 3987

UniProt: P48059