alpha KGDHC anticorps
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- Antigène Voir toutes alpha KGDHC (alphaKGDHC) Anticorps
- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp alpha KGDHC est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human OGDH (NP_001003941.1).
- Isotype
- IgG
- Top Product
- Discover our top product alphaKGDHC Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
- Autre désignation
- OGDH (alphaKGDHC Produits)
- Synonymes
- anticorps AKGDH, anticorps E1k, anticorps OGDC, anticorps 2210403E04Rik, anticorps 2210412K19Rik, anticorps AA409584, anticorps d1401, anticorps mKIAA4192, anticorps oxoglutarate dehydrogenase, anticorps oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide), anticorps OGDH, anticorps Ogdh
- Sujet
- This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Poids moléculaire
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Observed_MW: 116 kDa
Calculated_MW: 48 kDa/115 kDa
- ID gène
- 4967
- UniProt
- Q02218
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