RBP3 anticorps

N° du produit ABIN7262218

Détail du produit anti-RBP3 anticorps

Antigène: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBP3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RBP3 (NP_002891.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RBP3

Antigène: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Autre désignation: RBP3 (RBP3 Produits)

Synonymes: anticorps Irbp, anticorps Rbp-3, anticorps D10S64, anticorps D10S65, anticorps D10S66, anticorps IRBP, anticorps RBPI, anticorps RP66, anticorps retinol binding protein 3, anticorps interphotoreceptor retinoid-binding protein, anticorps retinol binding protein 3, interstitial, anticorps rbp3, anticorps RBP3, anticorps glr2547, anticorps XOO2681, anticorps AMED_0162, anticorps ambt_08395, anticorps Rbp3

Sujet: Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38 % identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Poids moléculaire:

Observed_MW: 180 kDa

Calculated_MW: 135 kDa

ID gène: 5949

UniProt: P10745