MXI1 anticorps

N° du produit ABIN7262545

Détail du produit anti-MXI1 anticorps

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MXI1 (NP_569157.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MXI1

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Autre désignation: MXI1 (MXI1 Produits)

Synonymes: anticorps mxi, anticorps mad2, anticorps mxd2, anticorps xmxi1, anticorps MGC89544, anticorps MXI1, anticorps etID309773.22, anticorps fb16b12, anticorps fb55f03, anticorps wu:fb16b12, anticorps wu:fb55f03, anticorps wu:fd06a08, anticorps wu:fz74f10, anticorps ENSMUSG00000067085, anticorps Gm10197, anticorps Mad2, anticorps bHLHc11, anticorps MXI-WR, anticorps MAD2, anticorps MXD2, anticorps MXI, anticorps MAX interactor 1, dimerization protein, anticorps max interactor 1, dimerization protein, anticorps MAX interactor 1, dimerization protein L homeolog, anticorps mxi1, anticorps MXI1, anticorps Mxi1, anticorps mxi1.L

Sujet: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Poids moléculaire:

Observed_MW: 35 kDa

Calculated_MW: 20 kDa/21 kDa/26 kDa/32 kDa

ID gène: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location