NPHP1 anticorps

N° du produit ABIN7262561

Détail du produit anti-NPHP1 anticorps

Antigène: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPHP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human NPHP1 (NP_001121651.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NPHP1

Antigène: NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))

Autre désignation: NPHP1 (NPHP1 Produits)

Synonymes: anticorps JBTS4, anticorps NPH1, anticorps SLSN1, anticorps nephrocystin-1, anticorps NPHP1, anticorps im:7162391, anticorps wu:fi59g07, anticorps zgc:152930, anticorps Nphp1, anticorps nephrocystin 1, anticorps nephronophthisis 1 (juvenile) homolog (human), anticorps nephronophthisis 1 (juvenile) L homeolog, anticorps nephronophthisis 1, anticorps nephrocystin-1, anticorps NPHP1, anticorps Nphp1, anticorps nphp1.L, anticorps nphp1, anticorps LOC100725987

Sujet: This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 83 kDa

Calculated_MW: 69 kDa/77 kDa/83 kDa

ID gène: 4867

UniProt: O15259