alpha Adaptin anticorps

N° du produit ABIN7262757

Détail du produit anti-alpha Adaptin anticorps

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adaptin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human AP2A1 (NP_055018.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur alpha Adaptin

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Autre désignation: AP2A1 (AP2A1 Produits)

Synonymes: anticorps ADTAA, anticorps AP2-ALPHA, anticorps CLAPA1, anticorps adtaa, anticorps clapa1, anticorps ap2-alpha, anticorps AP2A1, anticorps Adtaa, anticorps adaptor related protein complex 2 alpha 1 subunit, anticorps adaptor-related protein complex 2, alpha 1 subunit, anticorps AP-2 complex subunit alpha-1, anticorps AP2A1, anticorps ap2a1, anticorps Ap2a1, anticorps EDI_093420, anticorps EDI_259990

Sujet: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Poids moléculaire:

Observed_MW: 108 kDa

Calculated_MW: 105 kDa/107 kDa

ID gène: 160

UniProt: O95782

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation