PDE6B anticorps
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- Antigène Voir toutes PDE6B Anticorps
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDE6B est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human PDE6B (NP_001138763.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDE6B Anticorps primaire
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- Indications d'application
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
- Autre désignation
- PDE6B (PDE6B Produits)
- Sujet
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
- ID gène
- 5158
- UniProt
- P35913
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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