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PRKAB2 anticorps

PRKAB2 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7262869
  • Antigène Voir toutes PRKAB2 Anticorps
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Reactivité
    • 39
    • 19
    • 10
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 29
    • 9
    • 1
    Lapin
    Clonalité
    • 33
    • 6
    Polyclonal
    Conjugué
    • 28
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp PRKAB2 est non-conjugé
    Application
    • 35
    • 22
    • 19
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human PRKAB2 (NP_005390.1).
    Isotype
    IgG
    Top Product
    Discover our top product PRKAB2 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:100 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Autre désignation
    PRKAB2 (PRKAB2 Produits)
    Synonymes
    anticorps prkab2, anticorps MGC64365, anticorps PRKAB2, anticorps DKFZp469M1118, anticorps 5730553K21Rik, anticorps AW049591, anticorps BB124140, anticorps protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog, anticorps protein kinase AMP-activated non-catalytic subunit beta 2, anticorps protein kinase, AMP-activated, beta 2 non-catalytic subunit, anticorps prkab2.L, anticorps PRKAB2, anticorps prkab2, anticorps Prkab2
    Sujet
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
    ID gène
    5565
    UniProt
    O43741
    Pathways
    AMPK Signaling, L'effet Warburg
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