RAD51C anticorps

N° du produit ABIN7262879

Détail du produit anti-RAD51C anticorps

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RAD51C (NP_002867.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C (RAD51C Produits)

Synonymes: anticorps RGD1563765, anticorps CG2412, anticorps Dm CG2412, anticorps Dmel\\CG2412, anticorps zgc:101596, anticorps RAD51C, anticorps Rad51c, anticorps ATRAD51C, anticorps F4L23.21, anticorps RAS associated with diabetes protein 51C, anticorps R51H3, anticorps Rad51l2, anticorps BROVCA3, anticorps FANCO, anticorps RAD51L2, anticorps RAD51 paralog C, anticorps Rad51 recombinase D, anticorps Rad51 DNA recombinase 3, anticorps RAD51C protein, anticorps RAD51 homolog C, anticorps RAS associated with diabetes protein 51C, anticorps RAD51C, anticorps Rad51c, anticorps Rad51D, anticorps rad51c

Sujet: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

ID gène: 5889

UniProt: O43502

Pathways: Réparation de l'ADN