DPM1 anticorps

N° du produit ABIN7263775

Détail du produit anti-DPM1 anticorps

Antigène: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPM1 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DPM1 (NP_003850.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DPM1

Antigène: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Autre désignation: DPM1 (DPM1 Produits)

Synonymes: anticorps DPM1, anticorps zgc:101018, anticorps MGC114892, anticorps AI118379, anticorps AI194292, anticorps CDGIE, anticorps MPDS, anticorps DPMS, anticorps dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit, anticorps dolichyl-phosphate mannosyltransferase subunit 1, catalytic, anticorps dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog, anticorps dolichol-phosphate (beta-D) mannosyltransferase 1, anticorps dpm1, anticorps DPM1, anticorps dpm1.S, anticorps Dpm1

Sujet: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.

ID gène: 8813

UniProt: O60762

Pathways: Inositol Metabolic Process