anticorps C79673, anticorps Kindlin3, anticorps RGD1310168, anticorps MGC69069, anticorps MGC88900, anticorps KIND3, anticorps MIG-2, anticorps MIG2B, anticorps UNC112C, anticorps URP2, anticorps URP2SF, anticorps zgc:64101, anticorps fermitin family member 3, anticorps fermitin family member 3 L homeolog, anticorps fermitin family member 3b, anticorps Fermt3, anticorps fermt3.L, anticorps fermt3, anticorps FERMT3, anticorps fermt3b
Sujet
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.