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PDE6A anticorps

PDE6A Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7263957
  • Antigène Voir toutes PDE6A Anticorps
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Reactivité
    • 23
    • 9
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    Cet anticorp PDE6A est non-conjugé
    Application
    • 21
    • 17
    • 9
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human PDE6A (NP_000431.2).
    Isotype
    IgG
    Top Product
    Discover our top product PDE6A Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Autre désignation
    PDE6A (PDE6A Produits)
    Synonymes
    anticorps si:bz1d10.3, anticorps si:rp71-1d10.3, anticorps CGPR-A, anticorps PDEA, anticorps RP43, anticorps Pdea, anticorps nmf282, anticorps phosphodiesterase 6A, cGMP-specific, rod, alpha, anticorps phosphodiesterase 6A, anticorps pde6a, anticorps PDE6A, anticorps Pde6a
    Sujet
    This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
    Poids moléculaire

    Observed_MW: 120 kDa

    Calculated_MW: 99 kDa

    ID gène
    5145
    UniProt
    P16499
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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