Cofilin 2 anticorps

N° du produit ABIN7264069

Détail du produit anti-Cofilin 2 anticorps

Antigène: Cofilin 2 (CFL2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CFL2 (NP_068733.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: CFL2 (CFL2 Produits)

Synonymes: anticorps NEM7, anticorps CFL2, anticorps zgc:77288, anticorps cf12, anticorps cofilin 2, anticorps cofilin 2 (non-muscle), anticorps cofilin 2 (muscle), anticorps cofilin 2, muscle, anticorps cofilin-2, anticorps CFL2, anticorps cfl2, anticorps Cfl2, anticorps cf12, anticorps LOC100359205

Sujet: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 18 kDa

Calculated_MW: 16 kDa/18 kDa

ID gène: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis