TNK1 anticorps (AA 581-666) (Biotin)

N° du produit ABIN701217

Détail du produit anti-TNK1 anticorps (Biotin)

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Épitope: AA 581-666

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TNK1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TNK1

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Autre désignation: TNK1 (TNK1 Produits)

Synonymes: anticorps Kos1, anticorps Tnk1a, anticorps Tnk1b, anticorps Ack-like, anticorps tyrosine kinase non receptor 1, anticorps tyrosine kinase, non-receptor, 1, anticorps TNK1, anticorps Tnk1

Sujet:

Synonyms: CD38 negative kinase 1, EC 2.7.10.2 antibody Kinase of embryonic stem cells, Kos 1, Kos1, MGC46193, Non receptor tyrosine protein kinase TNK 1, Non receptor tyrosine protein kinase TNK1, Tnk 1, Tyrosine kinase non receptor 1.

Background: Tnk1 is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Tnk1 is a ubiquitously expressed 47- kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.

ID gène: 8711