anticorps Kcc3, anticorps ACCPN, anticorps KCC3, anticorps KCC3A, anticorps KCC3B, anticorps 9530023I19Rik, anticorps gaxp, anticorps solute carrier family 12, member 6, anticorps solute carrier family 12 member 6, anticorps Slc12a6, anticorps SLC12A6
Sujet
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.