EXOC2 anticorps
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- Antigène Voir toutes EXOC2 Anticorps
- EXOC2 (Exocyst Complex Component 2 (EXOC2))
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Reactivité
- Souris, Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EXOC2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human EXOC2 (NP_060773.3).
- Isotype
- IgG
- Top Product
- Discover our top product EXOC2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- EXOC2 (Exocyst Complex Component 2 (EXOC2))
- Autre désignation
- EXOC2 (EXOC2 Produits)
- Synonymes
- anticorps CG8843, anticorps Dmel\\CG8843, anticorps Sec-5, anticorps Sec5, anticorps Sec5p, anticorps dsec5, anticorps SEC5, anticorps SEC5L1, anticorps 2410030I24Rik, anticorps AI648199, anticorps Sec5l1, anticorps Rsec5, anticorps F7O12.2, anticorps F7O12_2, anticorps exocyst complex component sec5, anticorps Secretory 5, anticorps exocyst complex component 2, anticorps exocyst complex component sec5, anticorps Exocyst complex component 2, anticorps Sec5, anticorps EXOC2, anticorps Exoc2, anticorps SEC5A, anticorps sec-5
- Sujet
- The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
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Observed_MW: 108 kDa
Calculated_MW: 104 kDa
- ID gène
- 55770
- UniProt
- Q96KP1
- Pathways
- Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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