PER1 anticorps

N° du produit ABIN7264488

Détail du produit anti-PER1 anticorps

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PER1 (NP_002607.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PER1

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Autre désignation: PER1 (PER1 Produits)

Synonymes: anticorps PER, anticorps RIGUI, anticorps hPER, anticorps per1, anticorps si:ch211-237l4.4, anticorps Per, anticorps m-rigui, anticorps mPer1, anticorps rper1, anticorps Rigui-like, anticorps per4, anticorps zfper4, anticorps period circadian regulator 1, anticorps period circadian clock 1a, anticorps period circadian clock 1, anticorps period homolog 1 (Drosophila), anticorps period circadian clock 1b, anticorps PER1, anticorps per1a, anticorps per1, anticorps Per1, anticorps per1b

Sujet: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene, however, these variants have not been fully described.

ID gène: 5187

UniProt: O15534

Pathways: Photoperiodism