HIRA anticorps
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- Antigène Voir toutes HIRA Anticorps
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HIRA est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human HIRA (NP_003316.3).
- Isotype
- IgG
- Top Product
- Discover our top product HIRA Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
- Autre désignation
- HIRA (HIRA Produits)
- Sujet
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
- Poids moléculaire
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Observed_MW: 112 kDa
Calculated_MW: 89 kDa/111 kDa
- ID gène
- 7290
- UniProt
- P54198
- Pathways
- Chromatin Binding
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