Tppp anticorps

N° du produit ABIN7264631

Détail du produit anti-Tppp anticorps

Antigène: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tppp est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TPPP (NP_008961.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Tppp

Antigène: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Autre désignation: TPPP (Tppp Produits)

Synonymes: anticorps TPPP/p25, anticorps TPPP1, anticorps p24, anticorps p25, anticorps p25alpha, anticorps 2900041A09Rik, anticorps AI849835, anticorps RGD1310121, anticorps tubulin polymerization promoting protein, anticorps TPPP, anticorps Tppp

Sujet: Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Poids moléculaire:

Observed_MW: 24 kDa

Calculated_MW: 23 kDa

ID gène: 11076

UniProt: O94811